During ontogeny, the jaws increase in size, housing a developing dentition that increases in size and number, and all the while the jaw is required to adequately resist the biomechanical demands of mastication. My research therefore explores the coordinated development and evolution of the dentition and jaws, and how this integration may constrain the development of the masticatory system. The research uses a wide variety of methods including finite element analysis (FEA) and geometric morphometrics, in vivo electromyography and jaw kinematics, CT imaging and histology.
Baverstock H, Jeffery NS, Cobb SN (2013) The morphology of the mouse masticatory musculature. Journal of Anatomy, 223(1): 46-60
O'Higgins P, Fitton LC, Philips R, Shi J, Liu J, Groning F, Cobb SN, Fagan MJ (2012) Virtual functional morphology: novel approaches to the study of craniofacial form and function, Evolutionary Biology. DOI: 10.1007/s11692-012-9173-8
Meloro C, Raia P, Carotenuto F, Cobb SN (2011). Phylogenetic signal, function and integration in the subunits of the carnivoran mandible. Evolutionary Biology. 38(4): 465-475
Panagiotopoulou O & Cobb SN (2011). The mechanical significance of morphological variation in the macaque mandibular symphysis during mastication American Journal of Physical Anthropology. 146(2): 253-261
Cobb SN & Panagiotopoulou O (2011) Balancing the spatial demands of the developing dentition with the mechanical demands of the catarrhine mandibular symphysis. Journal of Anatomy. 218(1), 96-111
O'Higgins P, Cobb SN, Fitton LC, Groning F, Phillips R, Liu J, Fagan MJ (2011) Combining geometric morphometrics and functional simulation: an emerging toolkit for virtual functional analyses. Journal of Anatomy. 218(1), 3-15.
Panagiotopoulou O, Kupczik K, Cobb SN (2011). The mechanical function of the periodontal ligament in the macaque mandible: a validation and sensitivity study using finite element analysis.Journal of Anatomy. 218(1), 75-86.
Panagiotopoulou O, Curtis N, O’Higgins P, Cobb SN (2010) Modelling subcortical bone in finite element analyses: a validation and sensitivity study in the macaque mandible. Journal of Biomechanics, 43(8), 1603-1611. [Table 1 Erratum]
Cobb SN & Baverstock H (2009) Tooth root and craniomandibular morphological integration in the common chimpanzee (Pan troglodytes): alternative developmental models for the determinants of root length. In: Koppe T, Meyer G, Alt KW (Eds.) Comparative Dental Morphology.Frontiers of Oral Biology. Karger, Basel, 13: 121-127.
Cobb SN (2008) The facial skeleton of the chimpanzee-human last common ancestor. Journal of Anatomy, 212(4), 469-485.
Cobb SN & O'Higgins P (2007) The ontogeny of sexual dimorphism in the facial skeleton of the African apes. Journal of Human Evolution, 53, 176-190.
Strand Vidarsdottir U. & Cobb SN (2004) Inter- and intra-specific variation in the ontogeny of the hominoid facial skeleton: testing assumptions of ontogenetic variability. Annals of Anatomy, 186, 423-428.
Cobb SN & O’Higgins P (2004) Hominins do not share a common postnatal facial ontogenetic shape trajectory. Journal of Experimental Zoology(Molecular and Developmental Evolution), 302 B, 302-321.
Abstracts of Presentations at Scientific Meetings
Panagiotopoulou O, Kupczik K, Cobb SN (in press). The mechanical significance of the periodontal ligament in the macaque mandible: a validation and sensitivity study using ex vivo experimental analyses and finite element modelling. Journal of Morphology.
Cobb SN & Baverstock H (2010). Prognathism and the ontogeny of canine sexual dimorphism in Macaca mulatta. American Journal of Physical Anthropology 141 (S50), 82.
Panagiotopoulou O & Cobb SN (2010). The effect of the spatial demands of the developing dentition on the mechanical performance of the mandibular symphysis in juveniles. American Journal of Physical Anthropology 141 (S50)
Cobb SN & Baverstock H (2009) Integrated variation in facial orientation and the cranio-mandibular skeleton in the extant great apes. American Journal of Physical Anthropology 138 (S48), 107.
Panagiotopoulou O & Cobb SN (2009) Testing the adaptive significance of the catarrhine symphysis using Finite Element Analysis. American Journal of Physical Anthropology 138 (S48), 205.
O’Higgins P, Cobb SN, Fitton L, Groning F, Phillips R & Fagan MJ (2009) Facial mechanics in early hominins: a study combining geometric morphometrics and finite elements analysis. American Journal of Physical Anthropology 138 (S48), 201-202.
Cobb SN & Meloro, C. (2009) Fitting teeth in bending jaws: do the spatial demands of the developing dentition affect the utility of the mandible in reconstructing diet? Journal of Vertebrate Palaeontology 29, 80-81.
Panagiotopoulou, O. & Cobb, SN. (2009). Anterior mandibular morphology, masticatory biomechanics and dietary reconstructions of fossil hominoids. Journal of Vertebrate Palaeontology 29, 161.
Cobb SN & Willis, A. (2008) Is premaxilla morphology determined by the spatial requirements of the developing incisor dentition? American Journal of Physical Anthropology 135 (S46), 79-80.
Cobb SN & Baverstock H (2008) Facial orientation and a common pattern of craniomandibular integration in the extant great apes: taxonomic and adaptive implications for the Miocene hominoids.Workshop on European Fossil Primates, Simposio della Societa Paleontologica Italiana, Grosetto, Italy.
Panagiotopoulou O & Cobb SN (2008) Biomechanical adaptation in the mandibular symphysis of European Miocene hominoids.Workshop on European Fossil Primates, Simposio della Societa Paleontologica Italiana, Grosetto, Italy.
Cobb SN & Baverstock H (2008) Variation in the integrated craniomandibular skeleton and tooth root length: a test of an alternative developmental model of the determinants of root length. 14th International Symposium on Dental Morphology, Ernst Moritz Arndt University, Greifswald, Germany.
Panagiotopoulou O & Cobb SN (2008) Modelling trabecular and cortical bone in the macaque mandible: Do internal geometry and material properties matter? UK Workshop on Modern Functional Anatomy, Natural History Museum, London.
Panagiotopoulou O & Cobb SN (2008) Determinants of symphyseal form in mandible: Biomechanical and spatial models during ontogeny. Society for the Study of Human Biology, Oxford.
Cobb SN (2007). The face of the chimpanzee-human split: making inferences from the fossil evidence. Journal of Anatomy 210, 771.
Fujita M, Yamazaki K, O’Higgins P, Cobb S N & Dobney K (2005) The application of a new technique, geometric morphometrics, to the study of domestication and dispersal – On the teeth of Sus scrofa from archaeological sites. 59th Annual Meeting of the Anthropological Society of Nippon, Japan.
Cobb SN (2005) Odontoblast secretory activity: is developmental time a constraint? 5th UK Evolutionary Developmental Biology Conference, Manchester UK.
Vidarsdottir, U & Cobb, S (2004) Inter- and intra-specific variation in the ontogeny of the hominoid craniofacial skeleton. Folia primatologica 75(5), 354.
Cobb, SN & Dean, MC (2004) Odontoblast secretory activity: constrained by tooth identity or time? 8th International Conference on Tooth Morphogenesis and Differentiation, York, UK
Cobb, S & O’Higgins, P (2002). The ontogeny of form variation in the African ape facial skeleton: a hierarchical approach to the interspecific comparison of ontogenetic trajectories. American Journal of Physical Anthropology 117 (S34), 55.
Cobb, S & O’Higgins, P (2000). Cranial growth in extant African apes. American Journal of Physical Anthropology 111 (S30), 126.
Cobb, S & O’Higgins, P (1998). The growth of the cranial base in extant hominoids: a geometric morphometric study. Journal of Anatomy 192(2), 453.
Hennessy, R, O’Higgins, P & Cobb, S (1997). Three-dimensional studies of human craniofacial growth. Genetic Research (Cambridge) 70, 79.